Offered
Every other Spring semester.
Prerequisites and Registration Restrictions
11:115:403 General Biochemistry 11:115:413 Experimental Biochemistry.
For Pre-requisite overrides or Special Permission contact the Instructor.
Format
Two 80-minute lectures per week.
Description
Assay and purification of enzymes and other proteins. Chemical modification, site-directed mutagenesis, and enzyme kinetics as tools in understanding structure-function relationships and enzyme mechanisms. Mechanisms of selected enzymes.
Topics Covered
Enzyme kinetics, structure and function. Mechanisms of protein expression, modification and localization.
Course Book
No textbook required.
Learning Goals
Students will learn the details of enzyme kinetics, and how protein function is altered by expression, modification, and localization.
Examinations
Two short essay exams.
Other Requirements
Participation in course discussions. Oral presentation of current research articles.
Syllabus
A detailed syllabus will be available at the first class meeting and posted on the course Sakai page.