Course Synopsis:  Biochemistry of Cancer (SEBS)
11:115:421   (3 credits)

Offered:
This is a lecture course which is offered each Spring semester.

Prerequisites and Registration Restrictions:
Prerequisites: 11:115:403,404 General Biochemistry I and II. 

For Pre-requisite overrides or Special Permission contact the Instructor.

Format: 
Two 80 minute lectures per week.

Description:
Course covers the role of biochemical mechanisms in cancer, including DNA damage/repair mechanisms; oncogenes/tumor suppressor genes; signaling pathways; apoptosis/cell death; the cell cycle; metastasis-cell, cell contact, and protease activation; tumor growth and angiogenesis; genetic events; genetic polymorphisms; chemical carcinogenesis; chemotherapeutic targeting. The course is a 3 credit course, with lectures and student presentations of current research in the area.

Topics covered:  DNA damage/repair mechanisms; oncogenes/tumor suppressor genes; signaling pathways; apoptosis/cell death; the cell cycle; metastasis-cell, cell contact, and protease activation; tumor growth and angiogenesis; genetic events; genetic polymorphisms; chemical carcinogenesis; chemotherapeutic targeting

Course Book: The Biology of Cancer, Weinberg (2007)

Learning Goals: students will gain an understanding of the fundamental mechanism of cancer and cancer therapy, as well as gain experience in understanding and presenting current research in the cancer field.

Examinations:  Two short essay exams.

Other Requirements:  Students are expected to do one oral presentation on a recent research paper, and to write a final paper.

Syllabus:  A detailed syllabus will be available at the first class meeting and posted on the course Sakai page.

 

Additional Information: Contact Dr. Lori A. White, Rm 128, Lipman Hall, email: lawhite@aesop.rutgers.edu.